Novak Djokovic was eliminated in the first round of the US Open on Sunday after a grueling five set loss to unseeded Mariano Navone . Djokovic vomited on court, battled a cramp, received medical attention, and became emotional during the more than four hour match. Navone, ranked No. 48 in the world, stunned the 24 time Grand Slam champion with a 7 6, 5 7, 4 6, 6 2, 6 1 comeback. Djokovic appeared to be dealing with significant physical discomfort, taking medication provided by a doctor and receiving a back massage during a medical timeout. How Historic Was the Upset? Djokovic began crying in the fifth set while trailing 3 1, even as the New York crowd tried to rally him. The defeat marked Djokovic’s earliest Grand Slam exit in nearly two decades, dating back to his first round loss at the 2006 Australian Open. Novak Djokovic also lost in the opening round of the US Open for the first time in his career. Afterward, Djokovic offered a blunt assessment of the night: “I didn’t enjoy myself. I think it was obvious that it was an awful feeling on the court for me.”